教授
刘肖
博士
教授、博士生导师
生物与医学工程学院
北京市生物医学工程高精尖创新中心
北京航空航天大学
 

欢迎力学、物理、机械、自动化、材料、生命科学、生物医学工程类学科背景的同学报考

 

教育经历

2007.09-2012.01 北京航空航天大学 生物医学工程/高等工程 博士学位

2011.04-2011.07 英国帝国理工学院 化工系访学

2003.09-2007.07 北京航空航天大学 生物工程 学士学位

 

工作经历

2024.08-至今        北京航空航天大学 生物与医学工程学院 教授

2017.07-2024.08    北京航空航天大学 生物与医学工程学院 副教授

2012.01-2017.07      北京航空航天大学 生物与医学工程学院 讲师

2015.12-2016.12      哈佛大学医学院      访问学者

 

人才培养

北京市优秀毕业生(博士,硕士,本科)

第十七届“挑战杯”全国一等奖,第十一届“挑战杯”首都特等奖,“冯如杯 ”学生术科技作品竞赛获奖6

北京市优秀本科毕业论文,北航优秀硕士论文

北航“研究生十佳”,“沈元奖章”、“五四奖章,宝钢教育奖等

 

主要荣誉

中国科协“青年人才托举工程”

北京市优秀博士论文

北航优秀博士论文

北航青年拔尖人才

北航蓝天新秀

教育部学术新人奖

 

研究领域

心血管及其植介入体生物力学,血管组织再生,微流控技术和器官芯片

 

主要学术兼职

中国生物材料学会材料生物力学分会                   委员

中国心胸血管麻醉学会体外生命支持分会           青年委员

生物医学工程学杂志                                              青年编委

医用生物力学                                                          青年编委

Frontiers in Bioengineering and Biotechnology       编委

Medicine in Novel Technology and Devices            编委

Molecular & Cellular Biomechanics                         编委

 

主要学术论文(*通讯作者,#第一作者)

1.       Su H, Ma T, Liu X *, Wang L, Shu F, Liang Z, Zhang D, Zhang X, Li K, Wang M, Xin C, Zhang Y, Zhang J, Du Y, Fan Y*, Microfluidic organ chip of fluid–solid dynamic curved interface, Applied Physics Reviews, 2024, 11, 011404

2.       Ma T#, Liu X.#*, Su H#, Shi Q, He Y, Wu F, Gao C, Li K, Liang Z, Zhang D, Zhang X, Hu K, Li S, Wang L, Wang M, Yue S, Hong W, Chen X, Zhang J, Zheng L, Deng X, Wang P*, Fan Y*, Coupling of Perinuclear Actin Cap and Nuclear Mechanics in Regulating Flow-Induced Yap Spatiotemporal Nucleocytoplasmic Transport, Advanced Science, 2024, e2305867.

3.       Sun X, Li S, He Y, Liu Y, Ma T, Zeng R, Liu Z, Chen Y, Zheng Y*, Liu X*. Effects of cardiac function alterations on the risk of postoperative thrombotic complications in patients receiving endovascular aortic repair. Frontiers in Physiology 2023;13:2776.

4.       Li X, Liu X*, Liang Y, Deng X, Fan Y*. Spatiotemporal changes of local hemodynamics and plaque components during atherosclerotic progression in rabbit. Computer Methods Programs in Biomedicine 2022;220:106814.

5.       Li X, Liu X*, Deng X, Fan Y*. Interplay between Artificial Intelligence and Biomechanics Modeling in the Cardiovascular Disease Prediction. Biomedicines 2022;10(9):2157.

6.       Zhao P, Liu X*, Zhang X, Wang L, Su HR, Wang LY, He NX, Zhang DR, Li ZX, Kang HY, Sun AQ, Chen ZS, Zhou L, Wang M, Zhang YH, Deng XY*, Fan YB*. Flow shear stress controls the initiation of neovascularization via heparan sulfate proteoglycans within a biomimetic microfluidic model. Lab on a Chip 2021;21(2):421-34.

7.       Sun X, Ma T, Liu Z, Wu X, Zhang B, Zhu S, Li F, Chen M, Zheng Y*, Liu X*. Sequential numerical simulation of vascular remodeling and thrombosis in unconventional hybrid repair of ruptured middle aortic syndrome. Med Eng Phys 2021;94:87-95.

8.       Ma T, Zhang Z, Chen Y, Su H, Deng X, Liu X*, Fan Y*. Delivery of Nitric Oxide in the Cardiovascular System: Implications for Clinical Diagnosis and Therapy. Int J Mol Sci 2021;22(22).

9.       Ma T, Liu X*, Ren Q, Zhang Z, Sun X, Zheng Y, Deng X, Yu X*, Fan Y*. Flow-mediated dilation analysis coupled with nitric oxide transport to enhance the assessment of endothelial function. J Appl Physiol 2021;131(1):1-14.

10.    Han LZ, Ren Q, Lian JX, Luo LY, Liu HW, Ma TX, Li X, Deng XY*, Liu X*. Numerical analysis of the hemodynamics of rat aorta based on magnetic resonance imaging and fluid-structure interaction. Int J Numer Meth Biomed 2021;37(6):21.

11.    Yang, Y., Wang, H., Yang, H., Zhao, Y., Guo, J., Yin, X., Ma, T.*, Liu, X.* & Li, L.* 2020 Magnesium-Based Whitlockite Bone Mineral Promotes Neural and Osteogenic Activities. ACS Biomaterials Science & Engineering 6, 5785-5796.

12.    Wang, X.#, Liu, X. #, Bi, P., Zhang, Y., Li, L., Guo, J., Zhang, Y., Niu, X., Wang, Y. & Hu, L. 2020 Electrochemically Enabled Embedded Three-Dimensional Printing of Freestanding Gallium Wire-like Structures. Acs Applied Materials & Interfaces.

13.    Qian, S., Ma, T., Zhang, N., Liu, X.*, Zhao, P., Li, X., Chen, D., Hu, L., Chang, L. & Xu, L. 2020 Spatiotemporal transfer of nitric oxide in patient-specific atherosclerotic carotid artery bifurcations with MRI and computational fluid dynamics modeling. Computers in Biology and Medicine 125, 104015.

14.    Pi, Q.#, Maharjan, S. #, Yan, X. #, Liu, X. #, Singh, B., van Genderen, A.M., Robledo-Padilla, F., Parra-Saldivar, R., Hu, N., Jia, W., et al. 2018 Digitally Tunable Microfluidic Bioprinting of Multilayered Cannular Tissues. Adv Mater 30, e1706913.

15.    Zheng, Y. #, Liu, X. #, Xu, J., Zhao, H., Xiong, X., Hou, X. & Cui, J. 2017 Thermo-Responsive Mobile Interfaces with Switchable Wettability, Optical Properties, and Penetrability. Acs Appl Mater Interfaces 9, 35483-35491.

16.    Sheng, Z.Z. #, Liu, X. #, Min, L.L., Wang, H.L., Liu, W., Wang, M., Huang, L.Z., Wu, F. & Hou, X. 2017 Bioinspired approaches for medical devices. Chinese Chemical Letters 28, 1131-1134.

17.    Li, X. #, Liu, X. #, Zhang, P., Feng, C., Sun, A., Kang, H., Deng, X. & Fan, Y. 2017 Numerical simulation of haemodynamics and low-density lipoprotein transport in the rabbit aorta and their correlation with atherosclerotic plaque thickness. Journal of The Royal Society Interface 14, 20170140.

18.    Xue, Y., Liu, X.*, Sun, A., Zhang, P., Fan, Y. & Deng, X.* 2016 Hemodynamic Performance of a New Punched Stent Strut: A Numerical Study. Artif Organs 40, 669-677.

19.    Liu, X., Wang, L., Wang, Z., Li, Z., Kang, H., Fan, Y., Sun, A. & Deng, X. 2016 Bioinspired helical graft with taper to enhance helical flow. Journal of biomechanics 49, 3643-3650.

20.    Zhang, P., Liu, X.*, Sun, A., Fan, Y. & Deng, X.* 2015 Hemodynamic insight into overlapping bare-metal stents strategy in the treatment of aortic aneurysm. Journal of biomechanics 48, 2041-2046.

21.    Liu, X., Wang, M., Zhang, N., Fan, Z., Fan, Y. & Deng, X. 2015 Effects of endothelium, stent design and deployment on the nitric oxide transport in stented artery: a potential role in stent restenosis and thrombosis. Med Biol Eng Comput 53, 427-439.

22.    Liu, X., Sun, A., Fan, Y. & Deng, X. 2015 Physiological significance of helical flow in the arterial system and its potential clinical applications. Ann Biomed Eng 43, 3-15.

23.    Wang, Z.Z., Liu, X.*, Kang, H.Y., Sun, A.Q., Fan, Y.B. & Deng, X.Y.* 2014 Enhanced accumulation of LDLs within the venous graft wall induced by elevated filtration rate may account for its accelerated atherogenesis. Atherosclerosis 236, 198-206.

24.    Liu, X., Fan, Y., Sun, A. & Deng, X. 2013 Numerical simulation of nucleotide transport in the human thoracic aorta. Journal of biomechanics 46, 819-827.

25.    Liu, X., Fan, Y., Xu, X.Y. & Deng, X. 2012 Nitric oxide transport in an axisymmetric stenosis. Journal of the Royal Society, Interface 9, 2468-2478.

26.    Liu, X., Fan, Y. & Deng, X.Y. 2011 Mechanotransduction of flow-induced shear stress by endothelial glycocalyx fibers is torque determined. ASAIO Journal 57, 487-494.

27.    Liu, X., Fan, Y., Deng, X. & Zhan, F. 2011 Effect of non-Newtonian and pulsatile blood flow on mass transport in the human aorta. Journal of biomechanics 44, 1123-1131.

28.    Liu, X., Fan, Y. & Deng, X. 2011 Effect of the endothelial glycocalyx layer on arterial LDL transport under normal and high pressure. J Theor Biol 283, 71-81.

29.    Liu, X., Fan, Y. & Deng, X. 2010 Effect of spiral flow on the transport of oxygen in the aorta: a numerical study. Ann Biomed Eng 38, 917-926.

30.    Liu, X., Pu, F., Fan, Y., Deng, X., Li, D. & Li, S. 2009 A numerical study on the flow of blood and the transport of LDL in the human aorta: the physiological significance of the helical flow in the aortic arch. American journal of physiology. Heart and circulatory physiology 297, H163-170.

 

参看:http://scholar.google.com/citations?user=EblM8RUAAAAJ&hl=en

 

联系方式:

地址:北京市海淀区学院路37号,北京航空航天大学生物与医学工程学院

电子邮件: liuxiao@buaa.edu.cn