康红艳 博士
北京航空航天大学 生物与医学工程学院 副教授、博士生导师
Email: hongyankang@buaa.edu.cn
主要教育、科研简历:
2015 – 至今 北京航空航天大学、生物与医学工程学院、讲师、副教授
2008 – 2014 北京航空航天大学、生物与医学工程学院、工学博士
2012 – 2013 The City College of New York、Biomedical Engineering、Visiting students
2001 – 2004 重庆大学、生物工程专业、工学学士学位
Education
2008-2014: Ph.D. Biomedical Engineering, Beihang University, China
2012-2013: The City College of New York, Biomedical Engineering, Visiting students
2004-2008: Bachelor, Bioengineering, Chongqing University, China
Professional Experience
2015 – Present: Assistant Professor, School of Biological Science and Medical Engineering,
Beihang University, CHINA
主要研究方向:
1. 血管力学生物学
2. 糖萼:微观结构、力传导、与LDL相互作用、老化
3. 物质输运(低密度脂蛋白 )
Research Interests
1. Vascular Mechanobiology
2. Glycocalyx: structure, mechanotransduction, interact with LDL, aging
3. Mass transport (Low density lipoprotein)
学术荣誉: 北京航空航天大学第五批“青年拔尖人才”
近期主要论著(Recent Publications Selected):
1 Jiajia Liu, Hongyan Kang*, Xuejiao Ma, Anqiang Sun, Xiaoyan Deng, Yubo Fan*, Glycocalyx Mediated Vascular Remodeling Induced by Hemodynamic Environment Alteration, Hypertension, 2018,71(6): 1201-1209
2 Hongyan Kang, Jiajia Liu, Anqiang Sun, Xiao Liu, Yubo Fan*, Xiaoyan Deng*, Vascular smooth muscle cell glycocalyx mediates shear stress-induced contractile responses via a Rho kinase (ROCK)-myosin light chain phosphatase (MLCP) pathway, Scientific Reports, 2017, 7:42092
3 Hongyan Kang, Yubo Fan, Ping Zhao, Changhui Ren, Zhenze Wang, Xiaoyan Deng*, Regional Specific Modulation of the Glycocalyx and Smooth Muscle Cell Contractile Apparatus in Conduit Arteries of Tail-Suspended Rats, Journal of Applied Physiology, 2016, 120(5): 537-545
4 Hongyan Kang, Lianwen Sun, Yunfei Huang, Zhenze Wang, Ping Zhao, Yubo Fan*, Xiaoyan Deng*, Regional Specific Adaptation of the Endothelial Glycocalyx Dimension in Tail-Suspended Rats, Pflugers Archiv – European Journal of Physiology, 2015, 467: 1291-1301
5 Hongyan Kang, Limary M. Cancel, John M. Tarbell*, Effect of Shear Stress on Water and LDL Transport through Cultured Endothelial Cell Monolayers, Atherosclerosis, 2014, 233(2): 682-690
6 Hongyan Kang, Yubo Fan, Xiaoyan Deng*, Vascular Smooth Muscle Cell Glycocalyx Modulates Shear-Induced Proliferation, Migration, and NO Production Responses, American Journal of Physiology - Heart and Circulatory Physiology, 2011, 300(1): H76-H83
7 Hongyan Kang, Xuejiao Ma, Jiajia Liu, Yubo Fan*, Xiaoyan Deng*, High glucose-induced endothelial progenitor cell dysfunction, Diabetes & Vascular Disease Research, 2017, 1-14
8 Hongyan Kang, Meili Liu, Yubo Fan*, Xiaoyan Deng*, A Potential Gravity-Sensing Role of Vascular Smooth Muscle Cell Glycocalyx in Altered Gravitational Stimulation, Astrobiology, 2013, 13(7): 626-636
9 Hongyan Kang, Yubo Fan, Anqiang Sun, Xiaoling Jia, Xiaoyan Deng*, Simulated Microgravity Exposure Modulates the Phenotype of Cultured Vascular Smooth Muscle Cells, Cell Biochemistry and Biophysics, 2013, 66(1): 121-130
10 Hongyan Kang, Yubo Fan, Anqiang Sun, Xiaoyan Deng*, Compositional or Charge Density Modification of the Endothelial Glycocalyx Accelerates Flow-Dependent Concentration Polarization of Low-Density Lipoproteins, Experimental Biology and Medicine (Maywood), 2011, 236(7): 800-807
11 Zufeng Ding, Yubo Fan, Xiaoyan Deng, Anqiang Sun, Hongyan Kang. 3,3′-Dioctadecylindocarbocyanine-low-density lipoprotein uptake and flow patterns in the rabbit aorta–iliac bifurcation under three perfusion flow conditions. Experimental Biology& Medicine, 2010, 235(9): 1062-1071
12 Zufeng Ding, Yubo Fan, Xiaoyan Deng, Fan Zhan, Hongyan Kang. Effect of swirling flow on the uptakes of native and oxidized LDLs in a straight segment of the rabbit thoracic aorta. Experimental Biology & Medicine, 2010, 235(4): 506-513
13 Zhenze Wang, Xiao Liu, Hongyan Kang, Anqiang,Sun, Yubo Fan, Xiaoyan Deng. Enhanced accumulation of LDLs within the venous graft wall induced by elevated filtration rate may account for its accelerated atherogenesis. Atherosclerosis, 2014, 236(1):198-206
14 Tian Xiaopeng, Anqiang Sun, Liu Xiao, Fang Pu, Deng Xiaoyan, Hongyan Kang, Yubo Fan. Influence of catheter insertion on the hemodynamic environment in coronary arteries. Medical Engineering & Physics, 2016, 38(9):946
15 Xiao Liu, Libing Wang, Zhenze Wang. Zhengxing Li, Hongyan Kang, Yubo Fan, Anqiang Sun, Xiaoyan Deng. Bioinspired helical graft with taper to enhance helical flow. Journal of Biomechanics, 2016, 49(15): 3643-3650
16 Xili Ding, Tongqiang Zou, Xianghui Gong, Changhui Ren, Hongyan Kang, Peng Xu, Haifeng Liu, Yubo Fan. Trilayered sulfated silk fibroin vascular grafts enhanced with braided silk tube. Journal of Bioactive & Compatible Polymers, 2016, 31 (6)
17 Xili Ding, Chengqi Wu, Tong Ha, Lizhen Wang, Yan Huang, Hongyan Kang, Yingying Zhang, Haifeng Liu, Yubo Fan. Hydroxyapatite-containing silk fibroin nanofibrous scaffolds for tissue-engineered periosteum. Rsc Advances, 2016, 6(23): 19463-19474
18 Quan Zheng, Zhaowei chu, Xiaoming Li, Hongyan Kang, Xiao Yang, Yubo Fan. Effects of aqueous medium, tween-20 and flow on the stability of sirolimus. Journal of Mechanics in Medicine & Biology, 2017: 1750039
19 Xiaoyin Li, Xiao Liu, Peng Zhang, Chenglong Feng, Anqiang Sun, Hongyan Kang, Xiaoyan Deng, Yubo Fan. Numerical simulation of haemodynamics and low-density lipoprotein transport in the rabbit aorta and their correlation with atherosclerotic plaque thickness. Journal of the Royal Society Interface, 2017, 14(129): 20170140
20 康红艳,刘佳佳,喻淼淼,邓小燕*,血管内皮细胞糖萼的观测技术研究进展,生命科学,2016,28(9):1089~1099
21 康红艳,邓小燕*,混合脐血浆在人脐静脉内皮细胞培养中的应用潜力研究,生物医学工程学杂志,2011,(01):115 ~ 120
22 Hongyan Kang*, Xiaoyan Deng. The Endothelial Glycocalyx: Visualization and Measurement. Journal of Biomedicine, 2017, 2:120-123
23 邓小燕*,康红艳,血管内皮细胞糖萼与力传导,力学与实践,2010,32(1):1~ 9
联系方式:
地址:北京市海淀区学院路37号,北京航空航天大学生物与医学工程学院
邮编:100083
电子邮件: hongyankang@buaa.edu.cn
Contact Information:
Address: School of Biological Science and Medical Engineering, Beihang University
XueYuan Road No.37, HaiDian District, Beijing, 100083, China
Email: hongyankang@buaa.edu.cn |