王丽斌,学号SY1210120,系我院生物医学工程专业12级硕士研究生,于2013年7月15日在期刊《Journal of Nanomaterials》上发表题为《The Mutual Beneficial Effect between Medical Imaging and Nanomedicine》高水平学术论文一篇,该期刊影响因子为1.547。
The Mutual Beneficial Effect between Medical Imaging and Nanomedicine
Huiting Qiao,1 Libin Wang,1 Jintao Han,2 Yingmao Chen,3 Daifa Wang,1 and Deyu Li11 Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China
2 Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing, China3 Department of Nuclear Medicine, General Hospital of PLA, Beijing 100853, China
ABSTRACT
The reports on medical imaging and nanomedicine are getting more and more prevalent. Many nanoparticles entering into the body act as contrast agents, or probes in medical imaging, which are parts of nanomedicines. The application extent and the quality of imaging have been improved by nanotechnique. On one hand, nanomedicines advance the sensitivity and specificity of molecular imaging. On the other hand, the biodistribution of nanomedicine can also be studied in vivo by medical imaging, which is necessary in the toxicological research. The toxicity of nanomedicine is a concern which may slow down the application of nanomedical. The quantitative description of the kinetic process is significant. Based on metabolic study on radioactivity tracer, a scheme of pharmacokinetic research of nanomedicine is proposed. In this review, we will discuss the potential advantage of medical imaging in toxicology of nanomedicine, as well as the advancement of medical imaging prompted by nanomedicine.