王丽斌，学号SY1210120，系我院生物医学工程专业12级硕士研究生，于2014年9月16日在期刊《Journal of Bio-Medical Materials and Engineering》上发表题为《The effect of tumor size on the imaging diagnosis: A study based on simulation》高水平学术论文一篇，该期刊影响因子为0.847。

The effect of tumor size on the imaging diagnosis: A study based on simulation

Huiting Qiao, Libin Wang, Deyu Li, Daifa Wang and Yu Wang*

School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China

ABSTRACT

        Positron emission tomography (PET) has been widely used in early diagnosis of tumors. Though standardized uptake value (SUV) is a common diagnosis index for PET, it will be affected by the size of the tumor. To explore how the tumor size affects imaging diagnosis index, dynamic PET images were simulated to study the relationship between tumor size and the imaging diagnosis index. It was found that the SUV of the region of the tumor varied with scan time, and the SUV was always lower than the true value of tumor. Even more deviations were found in SUV with a reduced tumor size. The diagnosis index SUVmax was more reliable than SUV, for it declined only when the volume of tumor was less than 3mm3. Therefore, the effect of tumor size on the SUV and SUVmax that are used as diagnosis indices in the early diagnosis of tumors should not be neglected.

Keywords: Standardized uptake value, maximum standardized uptake value, positron emission tomography, tumor size, diagnosis