教授
齐颖新
生物与医学工程学院院长 教授、博士生导师
 

齐颖新 博士

北京航空航天大学 生物与医学工程学院  教授、博士生导师

 

Ying-Xin Qi, Ph.D. & Professor

Email:  qi_yx@buaa.edu.cn

 

主要教育、科研简历:

2018 – 至今 北京航空航天大学生物与医学工程学院   教授

2007 – 2018  上海交通大学生命科学技术学院  助理研究员/副研究员/教授

2011 – 2012  美国斯坦福大学生物工程系   访问学者

2004 – 2006  上海交通大学生物医学工程博士后流动站  博士后

2001 – 2004  西安交通大学医学院   医学博士

 

Education

2001 to 2004, M.D., School of Medicine, Xi'an Jiao Tong University, Xi'an, China

1994 to 2001, Bachelor of Medicine, School of Medicine, Xi'an Jiao Tong University, Xi'an, China

 

Professional Experience

2018 to present, Professor, School of Biological Science and Medical Engineering, Beihang University, Beijing, China

2014 to 2018, Professor, Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China

2009 to 2013, Associate professor, Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China

2011 to 2012, Visiting Scholar, Department of Bioengineering, Stanford University, Stanford, USA

2007 to 2008, Associate research fellow, Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China

2004 to 2006, Post doctor, Department of Biomedical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China                                                                                          

 

主要研究方向:

血管力学生物学

应力信号转导

血管蛋白质组学

 

Research Interests

Vascular Mechanobiology;

Mechanotranductio;

Vascular Proteomics

 

主要社会兼职:

中国力学学会中国生物医学工程学会生物力学专业委员会副主任委员

中国生物医学工程学会理事

中国生物生物化学与分子生物学学会理事

 

主要学术荣誉:

国家杰出青年科学基金(2016)

国家自然科学基金委优秀青年基金(2012)

教育部“新世纪优秀人才支持计划”(2009)

 

近期主要论著(通讯作者或第一作者):

1.     Bao H, Chen YX, Huang K, Zhuang F, Bao M, Han Y, Chen XH, Shi Q, Yao QP, Qi YX. Platelet-derived microparticles promote endothelial cell proliferation in hypertension via miR-142-3p. FASEB J, 2018;32(7):3912-3923.

2.     Bao H, Yao QP, Huang K, Chen XH, Han Y, Jiang ZL, Gao LZ, Qi YX. Platelet-derived miR-142-3p induces apoptosis of endothelial cells in hypertension. Cell Mol Biol (Noisy-le-grand). 2017;63(4):3-9.

3.     Yao QP, Xie ZW, Wang KX, Zhang P, Han Y, Qi YX, Jiang ZL. Profiles of long noncoding RNAs in hypertensive rats: long noncoding RNA XR007793 regulates cyclic strain-induced proliferation and migration of vascular smooth muscle cells. J Hypertens. 2017;35(6):1195-1203.

4.     Huang K, Bao H, Yan ZQ, Wang L, Zhang P, Yao QP, Shi Q, Chen XH, Wang KX, Shen BR, Qi YX, Jiang ZL. MicroRNA-33 protects against neointimal hyperplasia induced by arterial mechanical stretch in the grafted vein. Cardiovasc Res. 2017 Apr 1;113(5):488-497.

5.     Wang L, Bao H, Wang KX, Zhang P, Yao QP, Chen XH, Huang K, Qi YX, Jiang ZL. Secreted miR-27a Induced by Cyclic Stretch Modulates the Proliferation of Endothelial Cells in Hypertension via GRK6. Sci Rep. 2017;7:41058.

6.     Qi YX, Yao QP, Huang K, Shi Q, Zhang P, Wang GL, Han Y, Bao H, Wang L, Li HP, Shen BR, Wang Y, Chien S, Jiang ZL. Nuclear envelope proteins modulate proliferation of vascular smooth muscle cells during cyclic stretch application. Proc Natl Acad Sci USA. 2016; 113(19): 5293-8.

7.     Huang K, Yan ZQ, Zhao D, Chen SG, Gao LZ, Zhang P, Shen BR, Han HC, Qi YX, Jiang ZL. SIRT1 and FOXO Mediate Contractile Differentiation of Vascular Smooth Muscle Cells under Cyclic Stretch. Cell Physiol Biochem. 2015; 37(5): 1817-29.

8.     Chung EY, Ochs CJ, Wang Y, Lei L, Qin Q, Smith AM, Strongin AY, Kamm R, Qi YX, Lu S, Wang Y. Activatable and Cell-Penetrable Multiplex FRET Nanosensor for Profiling MT1-MMP Activity in Single Cancer Cells. Nano Lett. 2015; 15(8): 5025-32.

9.     Han Y, Wang L, Yao QP, Zhang P, Liu B, Wang GL, Shen BR, Cheng BB, Wang YX, Jiang ZL, Qi YX. Nuclear envelope proteins Nesprin2 and LaminA regulate proliferation and apoptosis of vascular endothelial cells in response to shear stress. BBA - Molecular Cell Research. 2015; 1853(5):1165-73.

10.  Wan XJ, Zhao HC, Zhang P, Huo B, Shen BR, Yan ZQ, Qi YX, Jiang ZL. Involvement of BK channel in differentiation of vascular smooth muscle cells induced by mechanical stretch. Int J Biochem Cell Biol. 2015; 59: 21-9. Yang YC, Wang XD, Huang Kai, Wang L, Jiang ZL, Qi YX. Temporal Phosphoproteomics to Investigate the Mechanotransduction of Vascular Smooth Muscle Cells in Response to Cyclic Stretch. J Biomech. 2014, 47(15): 3622-29.

11.  Cheng BB, Qu MJ, Wu LL, Shen Y, Yan ZQ, Zhang P, Qi YX, Jiang ZL. MicroRNA-34a targets Forkhead box j2 to modulate differentiation of endothelial progenitor cells in response to shear stress. J Mol Cell Cardiol. 2014; 74: 4-12.

12.  Wang XD, Huang JL, Yang L, Wei DQ, Qi YX, Jiang ZL. Identification of human disease genes from interactome network using graphlet interaction, PLoS One, 2014; 9(1): e86142.

13.  Wang L, Han Y, Shen Y, Yan ZQ, Zhang P, Yao QP, Shen BR, Gao LZ, Qi YX, Jiang ZL. Endothelial insulin-like growth factor-1 modulates proliferation and phenotype of smooth muscle cells induced by low shear stress. Ann Biomed Eng. 2014; 42(4): 776-86.

14.  Jiang J, Qi YX, Zhang P, Gu WT, Yan ZQ, Shen BR, Yao PQ, Kong H, Chien S, Jiang ZL. Involvement of Rab28 in NF-κB nuclear transport in endothelial cells. PLoS ONE. 2013; 8(2): e56076.

15.  Yao QP, Qi YX, Zhang P, Cheng BB, Yan ZQ, Jiang ZL. SIRT1 and Connexin40 Mediate the normal shear stress-induced inhibition of the proliferation of endothelial cells co-cultured with vascular smooth muscle cells. Cell Physiol Biochem. 2013; 31(2-3): 389-99.

16.  Yan ZQ, Li YQ, Cheng BB, Yao QP, Gao LZ, Gao QC, Gong XB, Qi YX, Jiang ZL. Effects of stretched vascular endothelial cells and smooth muscle cells on differentiation of endothelial progenitor cells. J Mech Med Biol. 2013; 13(2): 1350050 (12 pages).

17.  Cheng BB, Yan ZQ, Yao QP, Shen BR, Wang JY, Gao LZ, Li YQ, Yuan HT, Qi YX, Jiang ZL. Association of SIRT1 expression with shear stress induced endothelial progenitor cell differentiation. J Cell Biochem. 2012; 113: 3663-3671.

18.  Qi YX, Yao QP, Zhang P, Jiang ZL. RACK1 regulates Src activity on apoptosis of vascular smooth muscle cells induced by cyclic strain. Cel Mol Bioeng. 2011; 4(3): 358-367.

19.  Qi YX, Jiang J, Jiang XH, Wang XD, Ji SY, Han Y, Long DK, Shen BR, Yan ZQ, Chien S, Jiang ZL. PDGF-BB and TGFβ1 on cross-talk between endothelial and smooth muscle cells in vascular remodeling induced by low shear stress. Proc Natl Acad Sci USA. 2011; 108(5): 1908-1913.

 

联系方式:

地址:北京市海淀区学院路37号,北京航空航天大学生物与医学工程学院

邮编:100083

电子邮件: qi_yx@buaa.edu.cn

Contact Information:

Address:  School of Biological Science and Medical Engineering, Beihang University

XueYuan Road No.37, Beijing, 100083, China

Email:    qi_yx@buaa.edu.cn