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副教授
杜婧
职称职务:长聘副教授/博导
办公地点:逸夫馆
联系电话:010-8233
E-mail:dujing@buaa.edu.cn
 

北京航空航天大学 生物与医学工程学院  副教授/ 博士生导师 

Jing DU, Ph.D. & Associate Professor

School of Biological Science and Medical Engineering, Beihang University, Beijing, China

主要教育、科研简历

2000-2004  北京大学医学部、药学学士学位

2004-2009  清华大学生物科学与技术系/医学院、生物学博士学位

2009-2011  清华大学航天航空学院、博士后

2011-2013  清华大学航天航空学院、讲师

2013-2017    清华大学航天航空学院、副教授

2013-2014   东京大学(日本)、客座研究员

2017-至今  北京航空航天大学生物与医学工程学院、长聘副教授

Education / Professional Experience

2000-2004:      B.E., School of Pharmaceutical Sciences, Peking University, China 

2004-2009:      Ph.D., School of Medicine, Tsinghua University, China

2009-2011:      Postdoctoral RA, School of Aerospace, Tsinghua University, China

2011-2013:      Lecturer, School of Aerospace, Tsinghua University, China

2013-2017:      Associate Professor, School of Aerospace, Tsinghua University, China

2013-2014:      Visiting researcher, University of Tokyo, Japan

2007-Present:  Associate Professor, School of Biological Science and Medical Engineering, Beihang University, China

主要研究方向:

1.细胞与分子生物力学  2. 胚胎发育生物力学  3.生物医学工程 4. 干细胞工程学

Research Interests

1. Cellular and molecular biomechanics   2. Embryonic developmental biomechanics   3. Biomedical engineering 4. Stem cell engineering

主要研究工作简介:

近年来,先后主持国家自然科学基金青年基金和面上项目各1项、国家重点研发项目子课题1项。在相关领域发表SCI收录论文20余篇,获得国家发明专利2项。主要从事干细胞和胚胎发育生物力学,在细胞外力学微环境调控细胞命运的力学生物学机制方面进行了深入的研究。

社会兼职:

北京生物医学工程学会青年委员、

国际干细胞学会会员、

中国生物医学工程学会会员、

中国生物物理学会会员、

中国细胞生物学学会会员

主要教学工作简介:

  承担本科生和研究生专业课程的教学工作,主要包括《生物力学实验》、《多尺度生物力学》等课程,指导硕士研究生4名,协助指导博士研究生3名。

部分论文列表(Publications Selected):

1.       Xue Liu, Jing Du, Yang Shao, Shao-Fan Zhao, Ke-Fu Yao One-pot preparation of   nanoporous Ag-Cu@Ag core-shell alloy with enhanced oxidative stability and robust antibacterial activity. Scientific Reports 2017, 7, 10249

2.       Tailin Chen, Hucheng Zhao, Li Gao, Lichao Song, Fuchun Yang, Jing Du*. Hypotonicity promotes epithelial gap closure by lamellipodial protrusion. Progress in Biophysics and Molecular Biology 2017. In press

3.       Zi-Long Zhao#, Zong-Yuan Liu#, Jing Du, Guang-Kui Xu, and Xi-Qiao Feng A Dynamic Biochemomechanical Model of Geometry-Confined Cell Spreading. Biophysical Journal (2017) 112, 2377–2386

4.       Nana Luo, Jeffrey K. Weber, Shuang Wang, Binquan Luan, Hua Yue, Xiaobo Xi, Jing Du, Zaixing Yang, Wei Wei, Ruhong Zhou, Guanghui Ma PEGylated Graphene Oxide Elicits Strong Immunological Responses Despite Surface Passivation. Nature Communication 2017, 8, 14537

5.       Yuemiao Yin#, Jing Du#, Zhao Wang. Aβ metabolism and the role of ApoE in Alzheimer's disease, Alzheimer's Disease & Parkinsonism 2016, 6:285

6.       Jing Du#, Yan Zu#, Jing Li, Shuyuan Du, Yipu Xu, Lang Zhang, Li Jiang, Zhao Wang, Shu Chien*, Chun Yang*, Extracellular matrix stiffness dictates Wnt expression through integrin pathway, Scientific Reports, 2016, 6:20395, doi:10.1038 / srep20395

7.       Jing Du*, Yanlei Fan, Tailin Chen, Xiqiao Feng, Lifeact and Utr230 induce distinct actin assemblies in cell nuclei, Cytoskeleton, 2015,72 (11): 570–575

8.       Yan Zu, Xudong Liang, Jing Du, Shuai Zhou, Chun Yang*, Binding of integrin α1 to bone morphogenetic protein receptor IA suggests a novel role of integrin α1β1 in bone morphogenetic protein 2 signalling, Journal of Biomechanics, 2015, 48(14): 3950–3954

9.       Jing Du, Yan Zu, Yue Xu, Chun Yang*, ECM Stiffness Regulates Integrin Activity via FAK/Raf Pathway in a Negative Feedback Manner, Progress in Biochemistry and Biophysics, 2014, 41(11): 1155-1162

10.    Guangkui Xu, Chun Yang, Jing Du, Xiqiao Feng*, Integrin activation and internalization mediated by extracellular matrix elasticity: A biomechanical model, Journal of Biomechanics, 2014, 47(6):1479-1484

11.    Jing Du#, Yu Liang#, Feng Xu, Bing Sun, Zhao Wang*, Trehalose rescues Alzheimer’s disease phenotypes in APP/PS1 transgenic mice, Journal of Pharmacy and Pharmacology, 2013, 65(12):1753-1756

12.    Jing Du, Xiaofei Chen, Xudong Liang, Guangyao Zhang, Jia Xu, Linrong He, Qingyuan Zhan, Xi-Qiao Feng, Shu Chien*, Chun Yang*, Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity, PNAS, 2011, 108(23): 9466-9471

13.    Jing Du, Bing Sun, Kui Chen, Lang Zhang, Shubo Liu, Qingquan Gu, Li Fan, Nanming Zhao, Zhao Wang*, Metabolites of Cerebellar Neurons and Hippocampal Neurons Play Opposite Roles in Pathogenesis of Alzheimer's Disease, PLoS ONE, 2009, 4(5): e5530

14.    Jing Du, Lang Zhang, Shubo Liu, Chi Zhang, Xiuqing Huang, Jian Li, Nanming Zhao, Zhao Wang*, PPARgamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons, Biochemical and Biophysical Research Communications, 2009, 384(4): 357-361

15.     Jing Du, Bing Sun, Kui Chen, Li Fan, Zhao Wang*, Antagonist of peroxisome proliferator-activated receptor g induces cerebellar amyloid-b levels and motor dysfunction in APP/PS1 transgenic mice, Biochemical and Biophysical Research Communications, 2009, 384(3): 357-361

16.    Jing Du, Junlei Chang, Songxi Guo, Qing Zhang, Zhao Wang*, ApoE 4 Reduces the Expression of Abeta degrading enzyme IDE by Activating the NMDA Receptor in Hippocampal Neurons, Neuroscience Letters, 2009, 464(2): 140 – 145

 

联系方式:

地址:北京、北京航空航天大学、生物与医学工程学院

邮编:100191

Contact Information:

Address:  School of Biological Science and Medical Engineering, Beihang University

XueYuan Road No.37, HaiDian District, Beijing, 100191, China

Email:   dujing@buaa.edu.cn