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副教授
刘肖
博士,副教授,硕士生导师 北京航空航天大学 生物与医学工程学院 Liu xiao, Ph.D. & Associate Professor School of Biological Science and Medical Engineering, Beihang University
 

主要教育、工作简历:

2003.09-2007.07 北京航空航天大学 生物工程 学士学位
2007.09-2012.01 北京航空航天大学 生物医学工程/高等工程 博士学位

2011.04-2011.07 英国帝国理工学院 化工系访学

2012.01-2017.07 北京航空航天大学 生物与医学工程学院 讲师

2015.12-2016.12 哈佛大学医学院   访问学者

2017.07-至今   北京航空航天大学 生物与医学工程学院 副教授

 

Education & Professional Experience

2003.09-2007.07:Bachelor Biomedical Engineering, Beihang University

2007.09-2012.01:  Ph.D. Biomedical Engineering/Advanced Engineering, Beihang University

2011.04-2011.07  Visiting student, Chemical engineering, Imperial College London

2012.01-2017.07:  Lecturer, School of Biological Science and Medical Engineering, Beihang

2015.12-2016.12:  Visiting scholar, Harvard Medical School,

2017.07-Present:   Associate Professor, School of Biological Science and Medical Engineering

主要研究方向: 血流动力学、心血管系统中的物质传输、血管细胞中的力传导、微流控技术

Research Interests: Hemodynamics, Mass transport in the vascular system, Mechanotransduction in vascular cells, Microfluidics

主要荣誉: 中国科协“青年人才托举工程”,北京市优秀博士论文,北航优秀博士论文,北航青年拔尖人才,北航蓝天新秀,教育部学术新人奖。指导学生获得冯如杯科技竞赛二等奖、三等奖,大学生创新创业训练计划,京津冀生物医学工程‘新星杯’论文演讲大赛中二、三等奖,北航优秀毕业论文等。

主要论著(Publications Selected:

1. Liu X., Pu F., Fan Y., Deng X*., Li D., Li S. A numerical study on the flow of blood and the transport of LDL in the human aorta: the physiological significance of the helical flow in the aortic arch. American journal of physiology Heart and circulatory physiology. 2009, 297, H163-70.

2. Liu X., Fan Y., Deng X*. Effect of spiral flow on the transport of oxygen in the aorta: a numerical study. Ann Biomed Eng. 2010, 38, 917-26.

3. Liu X., Fan Y., Deng X*. Effect of the endothelial glycocalyx layer on arterial LDL transport under normal and high pressure. J Theor Biol. 2011, 283, 71-81.

4. Liu Xiao, Fan Yubo, Deng Xiaoyan. Mechanotransduction of flow-induced shear stress by endothelial glycocalyx fibers is torque determined. ASAIO Journal. 2011, 57, 487-94.

5. Liu X., Fan Y., Deng X., Zhan F. Effect of non-Newtonian and pulsatile blood flow on mass transport in the human aorta. Journal of biomechanics. 2011, 44, 1123-31.

6. Liu X., Fan Y., Xu X. Y., Deng X. Nitric oxide transport in an axisymmetric stenosis. Journal of the Royal Society, Interface / the Royal Society. 2012, 9, 2468-78.

7. Fan Zhenmin, Sun Anqiang*, Liu Xiao, Fan Yubo, Zhao Ping, Deng Xiaoyan*. The accelerated atherogenesis of venous grafts might be attributed to aggravated concentration polarization of low density lipoproteins: A numerical study. Journal of biomechanics. 2013, 46, 2388-93.

8. Liu X., Fan Y., Sun A., Deng X. Numerical simulation of nucleotide transport in the human thoracic aorta. Journal of biomechanics. 2013, 46, 819-27.

9. Liu X., Wang Z., Zhao P., Fan Z., Sun A., Zhan F., Fan Y., Deng X. Nitric oxide transport in normal human thoracic aorta: effects of hemodynamics and nitric oxide scavengers. PloS one. 2014, 9, e112395.

10. Wang Zhenze, Liu Xiao*, Kang Hongyan, Sun Anqiang, Fan Yubo, Deng Xiaoyan*. Enhanced accumulation of LDLs within the venous graft wall induced by elevated filtration rate may account for its accelerated atherogenesis. Atherosclerosis. 2014, 236, 198-206.

11. Xu M, Zhang C, Liu X, Li D*. Direct determination of cone-beam geometric parameters using the helical phantom. Physics in medicine and biology. 2014, 59, 5667.

12. Liu X., Sun A., Fan Y., Deng X. Physiological significance of helical flow in the arterial system and its potential clinical applications. Ann Biomed Eng. 2015, 43, 3-15.

13. Liu X., Wang M., Zhang N., Fan Z., Fan Y., Deng X. Effects of endothelium, stent design and deployment on the nitric oxide transport in stented artery: a potential role in stent restenosis and thrombosis. Med Biol Eng Comput. 2015, 53, 427-39.

14. Sun Anqiang, Tian Xiaopeng, Zhang Nan, Xu Zaipin, Deng Xiaoyan, Liu Ming, Liu Xiao*. Does lower limb exercise worsen renal artery hemodynamics in patients with abdominal aortic aneurysm? PloS one. 2015, 10, e0125121.

15. Sun A., Wang Z., Fan Z., Tian X., Zhan F., Deng X., Liu X*. Influence of proximal drug eluting stent (DES) on distal bare metal stent (BMS) in multi-stent implantation strategies in coronary arteries. Med Eng Phys. 2015, 37, 840-4.

16. Zhang P., Liu X*., Sun A., Fan Y., Deng X*. Hemodynamic insight into overlapping bare-metal stents strategy in the treatment of aortic aneurysm. Journal of biomechanics. 2015, 48, 2041-6.

17. Fan Z. M., Liu X*., Du C. F., Sun A. Q., Zhang N., Fan Z. M., Fan Y. B., Deng X. Y*. Plaque components affect wall stress in stented human carotid artery: A numerical study. Acta Mechanica Sinica. 2016, 32, 1149-54.

18. Li J., Tian X., Wang Z., Xiong J., Fan Y., Deng X., Sun A*., Liu X*. Influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA). Biomed Eng Online. 2016, 15, 135.

19. Liu X#., Wang L#., Wang Z., Li Z., Kang H., Fan Y., Sun A., Deng X. Bioinspired helical graft with taper to enhance helical flow. Journal of biomechanics. 2016, 49, 3643-50.

20. Tian Xiaopeng, Sun Anqiang*, Liu Xiao, Pu Fang, Deng Xiaoyan, Kang Hongyan, Fan Yubo*. Influence of catheter insertion on the hemodynamic environment in coronary arteries. Medical engineering & physics. 2016, 38, 946-51.

21. Xue Y., Liu X*., Sun A., Zhang P., Fan Y., Deng X*. Hemodynamic Performance of a New Punched Stent Strut: A Numerical Study. Artif Organs. 2016, 40, 669-77.

22. Fan Z., Liu X*., Sun A., Zhang N., Fan Y., Deng X*. Effect of longitudinal anatomical mismatch of stenting on the mechanical environment in human carotid artery with atherosclerotic plaques. Med Eng Phys. 2017, 114-9.

23. Kang H., Liu J., Sun A., Liu X., Fan Y*., Deng X*. Vascular smooth muscle cell glycocalyx mediates shear stress-induced contractile responses via a Rho kinase (ROCK)-myosin light chain phosphatase (MLCP) pathway. Sci Rep. 2017, 7, 42092.

24. Li X#., Liu X#., Zhang P., Feng C., Sun A., Kang H., Deng X*., Fan Y*. Numerical simulation of haemodynamics and low-density lipoprotein transport in the rabbit aorta and their correlation with atherosclerotic plaque thickness. Journal of The Royal Society Interface. 2017, 14, 20170140.

25. Liu W., Heinrich M. A., Zhou Y., Akpek A., Hu N., Liu X., Guan X., Zhong Z., Jin X., Khademhosseini A*., Zhang Y. S*. Extrusion Bioprinting of Shear-Thinning Gelatin Methacryloyl Bioinks. Advanced healthcare materials. 2017, 6,

26. Sheng Z. Z#., Liu X#., Min L. L., Wang H. L., Liu W., Wang M., Huang L. Z., Wu F., Hou X. Bioinspired approaches for medical devices. Chinese Chemical Letters. 2017, 28, 1131-4.

27. Zheng Y#., Liu X#., Xu J., Zhao H., Xiong X., Hou X., Cui J. Thermo-Responsive Mobile Interfaces with Switchable Wettability, Optical Properties, and Penetrability. Acs Appl Mater Interfaces. 2017, 9, 35483-91.

28. Zhu K*., Liu X., Li J*. Transcatheter aortic valve replacement in patients with high aortic anguation. Journal of thoracic disease. 2017, 9, S439-S41.

29. Zhu K#., Shin S. R#*., van Kempen T., Li Y. C., Ponraj V., Nasajpour A., Mandla S., Hu N., Liu X., Leijten J., Lin Y. D., Hussain M. A., Zhang Y. S., Tamayol A., Khademhosseini A*. Gold Nanocomposite Bioink for Printing 3D Cardiac Constructs. Advanced functional materials. 2017, 27,

30. De Nisco Giuseppe, Zhang Peng, Calò Karol, Liu Xiao, Ponzini Raffaele, Bignardi Cristina, Rizzo Giovanna, Deng Xiaoyan, Gallo Diego, Morbiducci Umberto*. What is needed to make low-density lipoprotein transport in human aorta computational models suitable to explore links to atherosclerosis? Impact of initial and inflow boundary conditions. Journal of biomechanics. 2018, 68, 33-42.

 

参看:http://scholar.google.com/citations?user=EblM8RUAAAAJ&hl=en

 

联系方式:

地址:北京市海淀区学院路37号,北京航空航天大学生物与医学工程学院 血流动力学实验室(412)

邮编:100191

电话:+86 10 82339962

电子邮件: liuxiao@buaa.edu.cn

Contact Information:

Address: Hemodynamics Lab, School of Biological Science and Medical Engineering, Beihang University

XueYuan Road No.37, HaiDian District, Beijing, China, 100191

Tel : +86 10 82339962

Email: liuxiao@buaa.edu.cn