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副教授
易宗春
博士 副教授
 

易宗春 博士

北京航空航天大学 生物与医学工程学院 副教授教授

 

Zong-Chun Yi, Ph.D. & Associate Professor

Department of Biological Science and Technology, School of Biological Science and Medical Engineering,Beihang University, Beijing

Tel:  86-10- 82339552

Email:  yizc@buaa.edu.cn

主要教育、科研简历

1988 - 1993    华中科技大学同济医学院(同济医科大学) 预防医学专业 学士学位

1993 - 1995    湖北民族学院 医学院 教师

1995 - 1998    华中科技大学同济医学院(同济医科大学) 毒理学专业 硕士学位

1998 - 2001    北京大学医学部 毒理学专业 博士学位

2001 - 2003    清华大学 生物科学与技术系 博士后

2004 - 2008    北京航空航天大学 生物工程系 副教授。

2008-         北京航空航天大学 生物与医学工程学院 副教授

Education

1998-2001:  Ph.D. Toxicology,  Peking University Health Science Center, China

1995-1998:  Master of Medical Science. Toxicology,Tongji Medical University, China

1988-1993:  B.M. Preventive Medicine,Tongji Medical University, China

Professional Experience

2008-Present:  Associate Professor, Department of Biological Science and Technology, School of BiologicalScience and Medical Engineering, Beihang University, China

2003-2008:     Associate Professor, Bioengineering Department, Beihang University, China

2001-2003:    Post-doctor, Department of Biological Science and Technology, Tsinghua University

1993-1995:     Teaching Assistant, Medical School of Hubei University of Nationalities

主要研究方向:

1.         航空航天医学与空间生命科学

2.         分子与细胞毒理学与药理学

3.         肿瘤生物学

Research Interests

1.         Aviation and Space Medicine and Space life Science

2.         Molecular and Celluar Toxicology and Pharmacology

3.         Tumor biology

主要社会兼职:

中华预防医学会卫生毒理专业委员会           委员。

 

Memberships of Professional Societies:

Committee member, Professional committee of Hygienic Toxicology, China Preventive Mediceine Association

主要学术荣誉:

北京航空航天大学蓝天计划科研类蓝天新星2005

北京市科技新星2006

近期主要论著(Recent Publications Selected:

[1]      Xiao-Fei Li, Xiao-Rong Wu, Ming Xue, Yan Wang, Jie Wang, Yang Li, Suriguga, Guang-Yao Zhang, Zong-Chun Yi*. The role of DNA methylation in catechol-enhanced erythroid differentiation of K562 cells. Toxicology and Applied Pharmacology. 2012; 265 (1): 43–50. http://dx.doi.org/10.1016/j.taap.2012.09.018.

[2]      Xiao-Rong Wu, Ming Xue, Xiao-Fei Li, Yan Wang, Jie Wang, Qing-Ling Han, Zong-Chun Yi*.Phenolic metabolites of benzene inhibited the erythroid differentiation of K562 cells. Toxicology Letters. 2011;203 (3): 190-199. doi:10.1016/j.toxlet.2011.03.012

[3]      Zong-Chun Yi*, Xiao-Fei Li, Yan Wang, Jie Wang, Yan Sun, Feng-Yuan Zhuang. The postmitoticSaccharomyces cerevisiae after spaceflight showed higher viability. Advances in Space Research.2011; 47 (11): 2049–2057. doi:10.1016/j.asr.2011.02.006.

[4]      Zong-Chun Yi, Bing Xia, Guang-Yao Zhang, Ming Xue, Hong Wang, Hui-Min Zhou, Yan Sun, Feng-Yuan Zhuang. Simulated microgravity inhibits the proliferation of K562 erythroleukemia cells but does not result in apoptosis. Advances in Space Research.2009; 44: 233-44. doi:10.1016/j.asr.2009.04.006

[5]      Zong-Chun Yi, Yan-Ze Liu, Hai-Xia Li, Zhao Wang. Chebulinic acid and tellimagrandin I inhibit DNA strand breaks by hydroquinone/Cu(II) and H2O2/Cu(II), but potentiate DNA strand breaks by H2O2/Fe(II).Toxicology in Vitro. 2009; 23(4): 667–673. doi:10.1016/j.tiv.2009.03.009

[6]      Zong-Chun Yi, Yan-Ze Liu, Hai-Xia Li, Zhao Wang. Prooxidant action of chebulinic acid and tellimagrandin I: causing copper-dependent DNA strand breaks. Toxicology in Vitro.2009; 23(3): 425–431. doi:10.1016/j.tiv.2009.01.012

[7]      Zong-Chun Yi, Hong Wang, Guang-Yao Zhang, Bing Xia. Downregulation of connexin 43 in nasopharyngeal carcinoma cells is related to promoter methylation. Oral Oncology. 2007; 43: 898-904.doi:10.1016/j.oraloncology.2006.11.004

[8]      Zong-chun Yi,Yan-Ze Liu, Hai-Xia Li, Yan Yin, Feng-Yuan Zhuang, Yu-Bo Fan, Zhao Wang.Tellimagrandin I enhances gap junctional communication and attenuates the tumor phenotype of human cervical carcinoma HeLa cells in vitro. Cancer Letters.2006; 242: 77-87. doi:10.1016/j.canlet.2005.10.044

[9]      Zongchun Yi, Zhao Wang, Haixia Li, Mingjie Liu. Inhibitory effect of tellimagrandin I on chemically induced differentiation of human leukemia K562 cells. Toxicol Letters. 2004; 147: 109–19.doi:10.1016/j.toxlet.2003.12.008

[10]    Zong-chun Yi, Zhao Wang, Hai-xia Li, Ming-jie Liu, Rong-cong Wu, Xiao-hui Wang. Inhibitory of Chebulinic Acid on Differentiation of Human Leukemia K562 Cells. Acta pharmacologica Sinica. 2004: 25(2): 231-8. http://www.chinaphar.com/1671-4083/25/231.pdf

[11]    Zong-chun Yi, Min Zhang, Juan-lin Fu, Zhao Wang, Zong-can Zhou. Down-Regulation of Mitotic Checkpoint Function in Transformed Human Embryo Lung Fibroblasts Induced by N-Methyl-N’-nitro-N-nitrosoguaridine. Chinese Medical Journal.2004; 117: 1079-83.http://www.cmj.org/Periodical/PDF/2004/200471079.pdf

[12]    Li-xue Zou, Shao-yan Cui, Jian Zhong, Zong-chun Yi, Yan Sun, Yu-bo Fan, Feng-yuan Zhuang.Upregulation of erythropoietin receptor in UT-7/EPO cells inhibits simulated microgravity-induced cell apoptosis. Advances in Space Research. 2011; 48 (2): 390–394. doi:10.1016/j.asr.2011.03.022

[13]    Chen Zhao, Yan Sun, Zong-Chun Yi, Long Rong, Feng-Yuan Zhuang, Yu-Bo Fan. Simulated microgravity inhibits cell wall regeneration of Penicillium decumbens protoplasts. Advances in Space Research.2010; 46: 701–6. doi:10.1016/j.asr.2010.04.026

[14]    Li-Xue Zou, Shao-Yan Cui, Jian Zhong, Zong-Chun Yi, Yan Sun, Yu-Bo Fan, Feng-Yuan Zhuang.Simulated microgravity induce apoptosis and down-regulation of erythropoietin receptor of UT-7/EPO cells. Advances in Space Research.2010; 46: 1237-44. doi:10.1016/j.asr.2010.04.026

[15]  Chi Wang, Chen Sang, Akira Higashibata, Noriaki Ishiok, Long Rong, Chun Yang, Yan Sun, Zong-Chun Yi, Feng-Yuan Zhuang. Changes of muscle-related genes and proteins after spaceflight in Caenorhabditis elegans. Progress in Biochemistry and Biophysics. 2008, 35(10): 1195-1201.

[16]  Chi Wang, Chen Sang, Chun Yang, Yan Sun, Zong-Chun Yi, Feng-Yuan Zhuang. Mechanisms of Muscular Atrophy and Gravisensing After Simulated Microgravity in Caenorhabditis elegans: Parallel Control to Spaceflight Research in C. elegans. Progress in Biochemistry and Biophysics. 2008, 35(11): 1298-1304. (In Chinese)

 

联系方式:

地址: 北京 北京航空航天大学 生物与医学工程学院

邮编: 100191

电话: 86-10- 82339552

Email:yizc@buaa.edu.cn

 

Contact Information:

Address: School of Biological Science and Medical Engineering, Beihang University

37 Xueyuan Road, HaiDian District, Beijing 100191, China

Tel:     86-10- 82339552

Email:   yizc@buaa.edu.cn