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副教授
贾潇凌

职称职务:副教授,硕士生导师
办公地点:逸夫馆310
联系电话:010-82314878
E-mail:jiaxiaoling@buaa.edu.cn
 

贾潇凌 博士

XiaoLing Jia, Ph.D.

School of Biological Science and Medical Engineering, Beihang University, Beijing

Email: jiaxiaoling@buaa.edu.cn

主要教育、科研简历:

1988 1992 山西大学、生物系、生物学专业、学士学位

1988 1995 山西大学、生物系、动物学专业、硕士学位

1995 2003 中国辐射防护研究院组织库、助理研究员

2003 2007 中国科学院力学研究所、国家微重力实验室、生物力学专业、博士

2003 –北京航空航天大学、生物与医学工程学院、讲师、副教授

Education and Professional Experience

1988-1992:  B.S. Biology, Shanxi University, China

1992-1995:  M.S. Zoology, Shanxi University, China

1995-2003:  Assistant researcher, Tissue Bank, China Institute for Radiation Protection

2003-2007:  Ph.D. Biomechanics, Institute Mechanics, China Academy of Science

2007-    :  Associate professor, lecturer, School of Biological Science and Medical Engineering, Beihang University

主要研究方向:

生物力学及力生物学

Research Interests

Biomechanics and Mechanobiology

近期主要论著(Recent Publications Selected:

1.         Fengxuan Han, Xiaoling Jia (贾潇凌), D Dai, et al Performance of a multilayered small-diameter vascular scaffold dual-loaded with VEGF and PDGF. Biomaterials.2013;34(30):7302-7312  (Co-first)

2.         Hong Zhang, Xiaoling Jia (贾潇凌), Fengxuan Han, et al Dual-Delivery of VEGF and PDGF by Double-layered Electrospun Membranes for for Blood Vessel Regeneration. Biomaterials. 2013;34(9):2202-2212  (Co-first)

3.         Xiaoling Jia (贾潇凌), Jingyun Yang, Wei Song,et al. Involvement of large conductance Ca2+-activated K+ channel in laminar shear stress-induced inhibition of vascular smooth muscle cell proliferation. pflugers archiv-european journal of physiology 2013;465(2):221-232

4.         Meiliang Li, Xiaoling Jia (贾潇凌), Jingyun Yang , Jianjun Deng and Guanghua Zhao. Effect of tannic acid on properties of soybean (Glycine max) seed ferritin: A model for interaction between naturally-occurring components in foodstuffs. Food Chemistry 2012;133:410-415 (Co-first)

5.         Chenyan Lv, Xiaoling Jia (贾潇凌), Meiliang Li, Jingyun Yang and Guanghua Zhao. Optimization of extraction process of crude protein from grape seeds by RSM. Food Science and Technology Research  2011;17:437-445   (Co-first)

6.         Xiaoling Jia (贾潇凌), Chenguang Zhao, Ping Li, et al. Sustained release of VEGF by coaxial electrospun dextran/PLGA fibrous membranes in vascular tissue engineering. Journal of biomaterial science-polymer edition.2011;22:1811-1827

7.         Xiaoling Jia (贾潇凌), Juan Chen and Mian Long. IL-8-induced L-selectin shedding regulates its binding kinetics to PSGL-1. Chinese Science Bulletin. 2009,54:2787-2793 

8.         Xin Gu, Xiaoling Jia (贾潇凌), Jiannan Feng, et al. Molecular modeling and affinity determination of scFv antibody: proper linker peptide enhances its activity. Annals of Biomedical Engineering 2010, 38:537-49. (Co-first)

9.         Xiaoling Jia (贾潇凌), Jingyun Yang, Liu Yang, Ping Li, Wei Song and Yubo Fan. Irrelevance of BK channel expression to VSMCs phenotype under shear stress. World congress on Medical physics and biomedical engineering, Beijing, china, may 2012:26-31.

10.     Li Wu, Botao Xiao, Xiaoling Jia(贾潇凌), et al. Impact of carrier stiffness and microtopology on two-dimensional kinetics of P-selectin and P-selectin glycoprotein ligand-1 interactions. Journal of biological chemistry 2007, 282:9846-9854 

11.     Mian Long, Xiaoling Jia. (贾潇凌) Selectin shedding regulates two-dimensional binding to PSGL-1. Biorheology 2008, 45:74-75 , 2008

12.     Yan Huang, Xiaoling Jia (贾潇凌),Ke Bai, et al. Effects of fluid shear stress on cardiomyogenic differentiation of rat bone marrow mesenchymal stem cells  Archives of medical research.2010 47:497-505.

13.     Ke Bai, Yan Huang, Xiaoling Jia(贾潇凌), et al. Endothelium oriented differentiation of bone marrow mesenchymal stem cells under chemical and mechanical stimulations. Journal of biomechanics 2010,43(6):1176-81

14.     Ping li, Xiaoliang Feng, Xiaoling Jia (贾潇凌)and Yubo Fan. Influences of Tensile Load on in vitro Degradation of Electrospun Poly(L-Lactide-co-Glycolide)Scaffold. Acta Biomaterialia  2010, 6:2991-29969

15.     Yu Zhang, Chen Sang, Katrin Paulsen, Andrea Arenz, Ziyan Zhao, Xiaoling Jia (贾潇凌), Oliver Ullrich, Fengyuan Zhuang. ICAM-1 expression and organization in human endothelial cells is sensitive to gravity Acta Astronautica 2010,1073-1080

16.     Xiao Botao; Tong Chunfang; Jia Xiaoling (贾潇凌), Guo Rui, Lv Shouqin Zhang Yan, McEver Rodger P., Zhu Cheng and  Long Mian. Tyrosine Replacement of PSGL-1 Reduces Association Kinetics with P- and L-Selectin on the Cell Membrane. Biophyical Journal 2012,103:777-785

17.     Yan Huang, Lisha Zheng, Xianghui Gong, Xiaoling Jia (贾潇凌), Wei Song, Meili Liu and Yubo Fan. Effect of Cyclic Strain on Cardiomyogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells. PLoS One. 2012;7(4):e34960.

18.      Zheng L, Huang Y, Song W, Gong X, Liu M, Jia X (贾潇凌), Zhou G, Chen L, Li A, Fan Y. Fluid shear stress regulates metalloproteinase-1 and 2 in human periodontal ligament cells: involvement of extracellular signal-regulated kinase (ERK) and P38 signaling pathways. J Biomech. 2012 21;45(14):2368-75.

19.     Xiao B, Tong C, Jia X (贾潇凌), Guo R, Lü S, Zhang Y, McEver RP, Zhu C, Long M. Tyrosine replacement of PSGL-1 reduces association kinetics with P- and L-selectin on the cell membrane. Biophys J. 2012;103(4):777-785.

20.     Ping Li, Lu Jia, Lizhen Liu, Chengguo Liu, Xiaoling Jia (贾潇凌)and Yubo Fan. Effects of electrical stimulation on growth of endothelial cell. World congress on Medical physics and biomedical engineering, IFMBE Proceedings 29 2013;192-195.

21.     Ping Li, Lizhen Liu, Lu Jia, Yanhui Song, Xiaoling Jia (贾潇凌)and Yubo Fan. Effects of tensile stimulation and electrical stimulation on the connexion-43 mRNA levels of cardiomyocytes in vitro. World congress on Medical physics and biomedical engineering, IFMBE Proceedings 29 2013;188-191.

22.     Wei Song, Yan Hang, Xiaoling Jia (贾潇凌), Xianghui Gong, Lisha Zheng and Yubo Fan. Trichostain A and shear stress in regulating endothelium differentiation of bone marrow mensenchymal stem cell. World congress on Medical physics and biomedical engineering, IFMBE Proceedings 29 2013;196-196.

23.     Hongyan Kang, Yubo Fan, Anqiang Sun, Xiaoling Jia (贾潇凌)and Xiaoyan Deng. Simulated Microgravity Exposure Modulates the Phenotype of Cultured Vascular Smooth Muscle Cells. Cell Biochemistry and Biophysics 2013;66(1):121-30

24.     Fan J, Jia X (贾潇凌), Huang Y, Fu BM, Fan Y. Greater scaffold permeability promotes growth of osteoblastic cells in a perfused bioreactor. J Tissue Eng Regen Med. 2013 doi: 10.1002/term.1701

25.     Wang J, Ma J, Dong L, Hou Y, Jia X (贾潇凌), Niu X, Fan Y Effect of anatase TiO2 nanoparticles on the growth of RSC-364 rat synovial cell. J Nanosci Nanotechnol. 2013;13(6):3874-9

26.     Liu M, Song W, Li P, Huang Y, Gong X, Zhou G, Jia X(贾潇凌), Zheng L, Fan . Galanin protects against nerve injury after shear stress in primary cultured rat cortical neurons PLoS One. 2013; 8(5):e63473.

27.     Liu L, Li P, Zhou G, Wang M, Jia X(贾潇凌), Liu M, Niu X, Song W, Liu H, Fan Y. Increased proliferation and differentiation of pre-osteoblasts MC3T3-E1 cells on nanostructured polypyrrole membrane under combined electrical and mechanical stimulation. J Biomed Nanotechnol. 2013 Sep;9(9):1532-9.

获得科研基金情况:

1.         国家自然科学青年基金IKca通道在周期性牵张致血管平滑肌细胞增殖、迁移及表型转变中的作用及机制研究90万,2014.01- 2017.12

2.         国家自然科学青年基金切应力对平滑肌细胞BKca通道的影响及β1β3整合素在其中所起的作用44万,2010.01- 2012.12

3.         教育部(博士点基金)炎症介质刺激下白细胞表面L-选择素的表达、分布和动力学变化的研究3.6万,2009.01-2011.12

联系方式:

地址:北京、北京航空航天大学、生物与医学工程学院

邮编:100191

电子邮件: jiaxiaoling@buaa.edu.cn

Contact Information:

Address:  School of Biological Science and Medical Engineering, Beihang University

XueYuan Road No.37, HaiDian District, Beijing, 100191, China

E-mail: jiaxiaoling@buaa.edu.cn